Author

F. Witzel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:statistical model· 1

Frequent Co-Authors

N. Bluthgen· 1 shared

Activity by Year

2018-2018 · peak 1/yr

1 paper

Recent·Most cited

When more is less: Dual phosphorylation protects signaling off-state against overexpression

F. Witzel, N. Bluthgen

The paper uses kinetic models to show that dual phosphorylation of Erk can lead to a bell-shaped response in Erk activity with increasing protein levels, protecting signaling from overactivation.

bioRxiv · Apr 5, 2018Biophysics