Feng Li

Artificial light at night and an invasive snail synergistically enhance the invasion of a non-native macrophyte

The paper investigates how artificial light at night and invasive snails interact to enhance the invasion of a non-native aquatic plant.

TEAD1 signaling modulates adrenal chromaffin maturation

The paper identifies TEAD1 signaling as a critical regulator of chromaffin cell differentiation and function, and shows that SB699551 modulates this signaling to suppress pheochromocytoma cell proliferation.

Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders

This study develops LD5095, a novel cereblon-recruiting RIPK1 degrader, showing potent RIPK1 degradation and tumor sensitization to immune checkpoint inhibitors.

Chemoproteomic Characterization of GPX4 Covalent Ligands and Targeted Degradation

The paper characterizes a covalent GPX4 inhibitor and develops degraders, expanding tools for GPX4 targeting.

CHAMP1 Complex Promotes Heterochromatin Assembly and Reduces Replication Stress

This study identifies the CHAMP1 complex as a regulator of heterochromatin assembly and replication fork stability, showing its role in preventing genomic instability in cancer cells.

MECP2 Duplication Uncouples Mitochondrial and Purine Metabolism During neuronal maturation

The paper identifies a disrupted mitochondrial-purine metabolism link in MECP2 Duplication Syndrome across multiple models, linking it to neurodevelopmental issues.

Alginate Oligosaccharides (from DP2 to DP9) Differentially Modulate Phytohormone Levels in Botrytis cinerea-Infected Wheat

This study evaluates how alginate oligosaccharides (AOS) of different chain lengths (DP 2-9) affect phytohormone levels in wheat infected with Botrytis cinerea, finding DP-dependent modulation of hormones like JA, SA, and ET.

The Effects of Alginate Oligosaccharides (AOS) with Degree of Polymerization (DP) 2, 3, 4, 5, 6, and 7 on Tomato Yields

This study shows that alginate oligosaccharides (AOS) with DP 2 and 3 increase tomato yield, fruit quality, and stress tolerance under greenhouse conditions.

Inferring non-coding RNA regulatory network from transcriptomic data and curated databases

The paper introduces CAR-NET, a framework for inferring non-coding RNA regulatory networks using transcriptomic data and curated databases, showing its effectiveness in simulations and case studies.

PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection

This study generates PCBP1 knockout pigs, which show reduced CSFV infection and provide a model for studying antiviral mechanisms.

Reduced Default Mode Network Functional Connectivity in Patients with Recurrent Major Depressive Disorder

The paper analyzes resting-state fMRI data from 1,300 MDD patients and 1,128 controls to find reduced default mode network functional connectivity in recurrent MDD, not first-episode MDD.