Author

Floric Slimani

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Édouard BertrandiD· 3 shared Oriane PourcelotiD· 3 shared Adham SafieddineiD· 2 shared Davide NormannoiD· 2 shared Dominique Barbieri-WeilliD· 2 shared Hervé Le HiriD· 2 shared Thomas BonteiD· 2 shared Thomas WalteriD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

Édouard BertrandORCID

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Author profile →

5 papers

Recent·Most cited

The elongation of Mest transcript into MestXL sustains, but does not initiate, the maternal allele bias of its convergent gene Copg2 during neurogenesis

Sophie Perillous, Anne-Charlotte Fromaget, Céline Gonthier‐Guéret, Ornella Clerici, Marion Espenel, Alice Murigneux, Sophie Phan, Léa Feit, Catherine Vaurs‐Barrière, Floric Slimani, Céline Lemmers, Davide Normanno, Amanda Ha, Nolan Ashworth, Aaron Bogutz, , Philippe Arnaúd

The paper investigates the regulation of maternal allele bias in Copg2 during neurogenesis, showing it involves a two-step mechanism beyond MestXL-mediated interference.

Nature Communications · Sep 23, 2026Peer-reviewedMolecular Biology

Co-translational determination of quaternary structures in chaperone factories

Manon Philippe, Soha Salloum, Floric Slimani, Davide Normanno, Isabelle Barbosa, Héloïse Chassé, Marie-Cécile Robert, Serge Urbach, Jacques Imbert, Martial Sevéno, Simon George, Hervé Le Hir, Séverine Boulon, Céline Verheggen, Édouard Bertrand

The paper identifies co-translational interactions between R2TP and client proteins, revealing a mechanism called co-translational chaperone channeling that facilitates early assembly of protein complexes.

Nature Communications · Jan 23, 2026Peer-reviewedCell Biology

A Deep Learning approach for time-consistent cell cycle phase prediction from microscopy data

Thomas Bonte, Oriane Pourcelot, Adham Safieddine, Floric Slimani, Florian Mueller, Dominique Barbieri-Weill, Édouard Bertrand, Thomas Walter

The paper predicts cell cycle phases from microscopy data using a variational auto-encoder with auxiliary tasks, and provides a new annotated dataset.

PLoS Computational Biology · Dec 11, 2025Peer-reviewedBioinformatics

Chemical inhibition of Exon Junction Complex assembly impairs mRNA localization and neural stem cells ciliogenesis

Tommaso Villa, Oriane Pourcelot, David Dierks, Marion Faucourt, Cindy Burel, Floric Slimani, Léa Guyonnet, Nathalie Spassky, Schraga Schwartz, Édouard Bertrand, Olivier Bensaude, Hervé Le Hir

This study shows that inhibiting EJC assembly with EJC-i disrupts mRNA localization and neural stem cell ciliogenesis by affecting multiple post-transcriptional processes.

Nucleic Acids Research · Nov 13, 2025Peer-reviewedMolecular Biology

Cell cycle-dependent mRNA localization in P-bodies

Adham Safieddine, Marie-Noëlle Benassy, Thomas Bonte, Floric Slimani, Oriane Pourcelot, Michel Kress, Michèle Ernoult-Lange, Maïté Courel, Emeline Coleno, Arthur Imbert, Antoine Laine, Annie Munier Godebert, Angelique Vinit, Corinne Blugeon, Guillaume Chevreux, , Dominique Weil

This study examines how mRNA localization to P-bodies changes during the cell cycle, revealing that mRNA dynamics in P-bodies are not solely linked to translation status but are regulated by RNA features and RBPs.

bioRxiv · Apr 16, 2024Cell Biology