Long-term Pannexin 1 ablation promotes structural and functional modifications in hippocampal neurons through the regulation of actin cytoskeleton and Rho GTPases activity.
Carolina Flores‐Muñoz, Francisca García-Rojas, Miguel A. Perez, Odra Santander, Elena Mery, Daniela López-Espíndola, Arlek M. González‐Jamett, Marco Fuenzalida, Agustı́n D. Martı́nez, Álvaro O. Ardiles
This study shows that Pannexin 1 ablation in adult hippocampal neurons leads to structural and functional changes, mediated by actin dynamics and Rho GTPase imbalance.
bioRxiv · Nov 3, 2021 · PreprintNeuroscience