Author

Frank Herweck

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Elke BurgermeisteriD· 2 shared Johannes BetgeiD· 2 shared Timo GaiseriD· 2 shared Tobias GuttingiD· 2 shared Veronika Hauber· 2 shared Adelheid CerwenkaiD· 1 shared Benedikt RauscheriD· 1 shared Bernd FischeriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Elke BurgermeisterORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Macrophages target PVR/CD155 on colorectal cancer cells via REVERBalpha

Dominik Kato, Yu Han, Laura Helm, Frank Herweck, Natalia Schichta, Lennart Malz, Katharina Herrmann, Mohammad Saad Farooq, Veronika Hauber, Tobias Gutting, Johannes Betge, Carsten Sticht, Timo Gaiser, Adelheid Cerwenka, Matthias P. A. Ebert, Elke Burgermeister

This study shows that macrophages target PVR/CD155 on colorectal cancer cells via REVERBα, suggesting a new therapeutic strategy for MSS+ CRC.

bioRxiv · Jan 29, 2026 · PreprintCancer Biology

The drug-induced phenotypic landscape of colorectal cancer organoids

Johannes Betge, Niklas Rindtorff, Jan Sauer, Benedikt Rauscher, Clara Dingert, Haristi Gaitantzi, Frank Herweck, Kauthar Srour-Mhanna, Thilo Miersch, Erica Valentini, Kim E. Boonekamp, Veronika Hauber, Tobias Gutting, Larissa Frank, Sebastian Belle, , Michael Boutros

This study uses image-based profiling and multi-omics integration to identify morphological axes of variation in colorectal cancer organoids and link them to biological mechanisms and drug responses.

Nature Communications · Jun 6, 2022Peer-reviewedGenomics