Systematic comparison of sequencing-based spatial transcriptomic methods
Yue You, Yuting Fu, Lanxiang Li, Zhongmin Zhang, Shikai Jia, Shihong Lu, Wenle Ren, Yifang Liu, Yang Xu, Xiaojing Liu, Fuqing Jiang, Guangdun Peng, Abhishek Sampath Kumar, Matthew E. Ritchie, Xiaodong Liu, Luyi Tian
This study compares six sequencing-based spatial transcriptomic methods using reference tissues, highlighting molecular diffusion as a key variable affecting resolution and identifying unique attributes of spatial transcriptomic data.
Nature Methods · Jul 4, 2024Peer-reviewedGenomics