MicrobiologybioRxiv
Nutrient limitation magnifies fitness costs of antimalarial drug resistance mutations
S. K. Nair, X. Li, G. A. Arya…·T. J. Anderson
This study shows that fitness costs of antimalarial drug resistance mutations are significantly higher in nutrient-limited media compared to standard RPMI, suggesting underestimation in typical lab conditions.
DOI 10.1128/aac.01529-21