Cancer BiologybioRxivPreprint
Uncovering the modified immunopeptidome reveals insights into principles of PTM-driven antigenicity
A. Kacen, A. Javitt, M. P. Kramer…·Y. Merbl
The paper identifies thousands of novel cancer-specific antigens by analyzing PTMs in immunopeptidomics data from multiple sources and reveals their impact on HLA binding and TCR recognition.