In-solution buffer-free digestion for the analysis of SARS-CoV-2 RBD proteins allows a full sequence coverage and detection of post-translational modifications in a single ESI-MS spectrum
L. A. Espinosa, Y. Ramos, I. Andujar, E. O. Torres, G. Cabrera, A. Martin, D. Gonzalez, G. Chinea, M. Becquet, I. Gonzalez, C. Canaan-Haden, E. Nelson, G. Rojas, B. Perez-Masson, D. Perez-Martinez, , L. J. Gonzalez
This paper introduces an in-solution buffer-free digestion method for analyzing SARS-CoV-2 RBD proteins, achieving full sequence coverage and detecting post-translational modifications in a single ESI-MS spectrum.
bioRxiv · May 10, 2021 · PreprintBiochemistry