BiochemistrybioRxivPreprint
Tuning aromatic contributions by site-specific encoding of fluorinated phenylalanine residues in bacterial and mammalian cells
G. D. Galles, D. T. Infield, C. J. Clark…·C. A. Ahern
This paper introduces new pyrrolysine-based aminoacyl-tRNA synthetase/tRNA pairs to site-specifically encode fluorinated phenylalanine residues in bacterial and mammalian cells, enabling experimental assessment of aromatic-pi interactions.