Author

G. Eick

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Evolutionary Biology· 1

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Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

C. D. Okafor· 1 shared D. Hercules· 1 shared E. A. Ortlund· 1 shared J. K. Colucci· 1 shared J. W. Thornton· 1 shared K. Cottrill· 1 shared M. L. Cato· 1 shared S. H. Khan· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperEvolutionary Biology

C. D. Okafor

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1 paper

Recent·Most cited

Evolutionary tuning of a key helix drove androgen selectivity

C. D. Okafor, J. K. Colucci, M. L. Cato, S. H. Khan, K. Cottrill, D. Hercules, G. Eick, J. W. Thornton, E. A. Ortlund

The paper investigates how evolutionary changes in helix 10 of androgen receptors drove ligand selectivity by analyzing ancestral proteins and biophysical mechanisms.

bioRxiv · Jul 21, 2021 · PreprintEvolutionary Biology