Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus.
S. DebRoy, V. A. Tobar, G. Galvez, S. Arora, X. Liang, N. M. Horstmann, V. Maracaja-Coutinho, M. Latorre, M. Hook, A. R. Flores, S. Shelburne
This study identifies the in vivo DNA binding profile of CcpA in group A Streptococcus and shows that HPr is required for CcpA-mediated regulation and DNA binding.
Molecular Microbiology · Jun 1, 2021Peer-reviewedMicrobiology