The Clostridioides difficile S-Layer Protein A (SlpA) serves as a general phage receptor
A. L. M. Royer, A. A. Umansky, M.-M. Allen, J. R. Garneau, M. O. Bedoya, J. A. Kirk, G. Govoni, R. P. Fagan, O. Soutourina, L.-C. Fortier
This paper demonstrates that SlpA is a common receptor for multiple C. difficile phages, enabling the rational design of phage cocktails.
bioRxiv · Sep 19, 2022Microbiology