BK channels have opposite effects on sodium versus calcium-mediated action potentials in endocrine pituitary cells.
G. Halnes, S. Tennoe, T. M. Haug, G. T. Einevoll, F.-A. Weltzien, K. Hodne
The paper develops a computational model of medaka gonadotrope cells that fire INa-mediated action potentials and compares it to a rat model, finding that BK channels have opposite effects on AP duration depending on the underlying current mechanism.
bioRxiv · Nov 23, 2018Cell Biology