Nepicastat, a dopamine-beta-hydroxylase inhibitor decreases blood pressure and induces the infiltration of macrophages and B cells in the heart of spontaneous hypertensive rats
Nepicastat reduces systolic blood pressure and intraventricular septal thickness in SHR rats but increases macrophage and B cell infiltration in the heart.
bioRxiv · Jul 28, 2023 · PreprintPharmacology & Toxicology