Effect of Cellular and ECM Aging on Human iPSC-derived Cardiomyocyte Performance, Maturity and Senescence
G. Ozcebe, G. Bahcecioglu, X. Yue, P. Zorlutuna
This study examines how cellular and ECM aging affect iPSC-derived cardiomyocyte function, maturity, and stress response, finding that ECM aging accelerates cellular aging and impairs cardiac function.
bioRxiv · Sep 28, 2020Bioengineering