Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity
W. S. DeWitt, A. Smith, G. Schoch, J. A. Hansen, F. A. Matsen, P. H. Bradley
The paper analyzes TCR repertoire data to uncover associations between MHC alleles, immune exposures, and TCR sequences in a human cohort, revealing patterns linked to pathogen exposure and genetic background.
bioRxiv · May 2, 2018Immunology