G. Vaaje-Kolstad

Calcium binding site in AA10 LPMO from Vibrio cholerae suggests modulating effects during environment survival and infection

The paper identifies a calcium-binding site in GbpA from V. cholerae that influences protein stability and substrate binding during environmental survival and infection.

Revisiting the activity of two poly(vinyl chloride)- and polyethylene-degrading enzymes

This study attempts to replicate two recent claims of enzymatic degradation of polyethylene and poly(vinyl chloride) but finds no activity under various conditions, suggesting previous results may have been misinterpreted.

Tangled up in fibers: How a lytic polysaccharide monooxygenase binds its chitin substrate

This paper investigates how the LPMO GbpA binds to chitin, showing it spreads on fibers and forms clumps, aiding bacterial microcolony formation.

Biochemical and structural characterisation of a family GH5 cellulase from endosymbiont of shipworm P. megotara

This study characterizes a GH5 cellulase from a shipworm endosymbiont, showing synergistic activity with LPMO on crystalline cellulose and revealing a unique substrate binding cleft.

The gastric mucosa of Atlantic salmon (Salmo salar) is abundant in highly active chitinases

The paper identifies and characterizes three chitinase genes in Atlantic salmon, showing their abundance and activity in the gastric mucosa.

The fish pathogen Aliivibrio salmonicida LFI1238 can degrade and metabolize chitin despite major gene loss in the chitinolytic pathway

This study shows that Aliivibrio salmonicida LFI1238 can degrade and metabolize chitin despite having many chitinolytic genes disrupted, using GH18 chitinase and AA10 LPMOs for this ability.

Fenton-type chemistry by a copper enzyme: molecular mechanism of polysaccharide oxidative cleavage

This study identifies H2O2 as the co-substrate for LPMOs, revealing a mechanism for polysaccharide oxidative cleavage and improving enzymatic stability and activity.