TRIM28 preserves ovarian identity by stabilising lineage-specific transcription factor hubs
Laura Sitkiewicz, Florian Chaleil, Gaby Granes, Moïra Rossitto, Stephanie Déjardin, Florence M. Cammas, Anne‐Marie Lefrançois‐Martinez, Isabelle Stévant, Françis Poulat
This study identifies TRIM28's role in preserving ovarian identity by stabilizing lineage-specific transcription factor hubs rather than through H3K9me3-dependent heterochromatin.
bioRxiv · Jul 27, 2026 · PreprintGenomics