A conserved Foxp1-Pde4d axis regulates inflammatory responsiveness
Loes M. H. Elemans, Panna Tandon, Gavin Rodger, Lauren Stirling, Samantha Hendry, Muhammad Nadeem Akhtar, Xinyi Chen, Tijana Mitić, Yi Feng, Robert K. Semple, James E. N. Minchin
This study identifies a conserved Foxp1-Pde4d regulatory axis that preserves inflammatory responsiveness by controlling cAMP signaling across vertebrate species.
bioRxiv · Oct 30, 2026 · PreprintCell Biology