Systems BiologybioRxivPreprint
Protein context shapes the specificity of domain-peptide interactions in vivo
Ugo Dionne, Émilie Bourgault, Alexandre K. Dubé…·Christian R. Landry
The paper shows that SH3 domain specificity in PPIs is influenced by host protein identity and domain position, not just intrinsic domain properties.
DOI 10.1101/2020.05.18.103002