Comparable daughter radionuclide redistribution with superior tumor absorbed dose of the SSTR2 antagonist Ac-DOTA-TATE
Prachi Bharat Desai, Marion Huber, Dennis Mewis, Nicolas Chouin, Manuel Sturzbecher‐Hoehne, Germo Gericke, Anika Jaekel
This study compares tumor absorbed dose and daughter radionuclide redistribution between SSTR2 antagonist and agonist radioligands, finding superior tumor dose for the antagonist despite minimal internalization.
bioRxiv · Mar 18, 2026 · PreprintCancer Biology