Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females
Abraham Grant Shain, Clarissa Savko, Sophie Rokaw, Faid Jaafar, Abigail Rieder, Morgan Wright, Joy A. Phillips, Nickolas Konja, Sama Michael, Haley Mathews, Gina Jerjees, Barbara Bailey, Mark Alan Sussman
This study shows nicotine in vape aerosol induces p16 expression and collagen deposition in male cardiac tissue but not females, while vape alone increases fibroblasts without collagen changes.
bioRxiv · Aug 1, 2024 · PreprintMolecular Biology