Cortical projection neurons exhibit early maturation defects and selective degeneration in a mouse model of spinal muscular atrophy
Roberta Schellino, Federica La Rocca, Giulia Iezzi, Anna Caretto, Marina Boido, Alessandro Vercelli
This study identifies early maturation defects and selective degeneration of cortical projection neurons in a mouse model of SMA, highlighting cortical pathology beyond lower motor neurons.
bioRxiv · Oct 11, 2026 · PreprintNeuroscience