Establishment and stability of the latent HIV-1 DNA reservoir
Johanna Brodin, Fabio Zanini, Lina Thebo, Christa Lanz, Goran Bratt, Richard Neher, Jan Albert
The paper analyzes HIV-1 DNA reservoirs during suppressive ART and finds that most viral DNA sequences are similar to pre-treatment RNA sequences, suggesting ART halts viral turnover rather than persistent replication.
bioRxiv · May 23, 2016Microbiology