Lef1 Promotes Foxi1-Dependent Ionocyte Specification by Airway Submucosal Gland Progenitors
Weam S. Shahin, Javahir Hajibabazade, Olivia Snyder, Grace Fritz, Feng Yuan, Vitaly Ievlev, Thomas J. Lynch, Charles A. Yeaman, John F. Engelhardt
This study identifies Lef1 as a key factor promoting ionocyte specification from submucosal gland progenitors, with Foxi1 playing a regulatory role in this process.
bioRxiv · Oct 16, 2026 · PreprintCell Biology