Author

Grant W. Larson

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Anoop Rama DamodaraniD· 2 shared Eaindra YeeiD· 2 shared Ambika Bhagi‐DamodaraniD· 1 shared Edward Hoey· 1 shared Elizabeth A. Apiche· 1 shared Hideki AiharaiD· 1 shared Ke ShiiD· 1 shared Murphi T. WilliamsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

Anoop Rama DamodaranORCID

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2 papers

Recent·Most cited

Immunoblot-based activity assay for heme-containing histidine kinases

Grant W. Larson, Eaindra Yee, Anoop Rama Damodaran

The paper introduces an immunoblot-based activity assay using a near-IR fluorophore-labeled antibody to measure heme-containing histidine kinase activity, overcoming interference from heme fluorescence.

JBIC Journal of Biological Inorganic Chemistry · Apr 29, 2026Peer-reviewedBiochemistry

Rational design of tertiary coordination sphere of a heme-based sensor for two-orders enhanced oxygen affinity

Anoop Rama Damodaran, Eaindra Yee, Rahul L. Khade, Murphi T. Williams, Elizabeth A. Apiche, R. Hunter Wilson, Edward Hoey, Grant W. Larson, Ke Shi, Hideki Aihara, Yong Zhang, Ambika Bhagi‐Damodaran

This study enhances the oxygen affinity of the DosS protein by modifying its heme coordination sphere, achieving a 150-fold increase in O2 binding affinity.

bioRxiv · May 27, 2025 · PreprintBiochemistry