Sbh1/Sec61beta is a specific signal peptide receptor within the Sec61 channel
Lalitha Yadhanapudi, Mark Lommel, Pratiti Bhadra, Guido Barbieri, Richa Singh, Martin Jung, Volkhard Helms, Terese Eisgruber, Florian Stengel, Arne Boergel, Kim Remans, Karin Römisch
This study identifies Sbh1/Sec61β as a specific signal peptide receptor that recognizes and guides substrates into the Sec61 channel through its cytosolic IDR and conserved regions.
bioRxiv · Mar 12, 2024 · PreprintBiochemistry