Phosphorylation of GMFγ by c-Abl coordinates lamellipodial and focal adhesion dynamics
Brennan D. Gerlach, Guoning Liao, Kate Tubbesing, Alyssa C. Rezey, Ruping Wang, Margarida Barroso, Dale D. Tang
This study shows that c-Abl phosphorylates GMFγ at tyrosine-104, directing N-WASP to either protrusions or focal adhesions, thereby regulating cell migration.
bioRxiv · Jan 16, 2018 · PreprintCell Biology