Author

Brennan D. Gerlach

Columbia University Irving Medical CenterORCID 0000-0002-2791-3534Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alyssa C. Rezey· 1 shared Arif YurdaguliD· 1 shared Arun Jayant SanyaliD· 1 shared Bradley A. ZinkeriD· 1 shared Chyuan‐Sheng LiniD· 1 shared D. Christopher SloasiD· 1 shared Dale D. TangiD· 1 shared Eui Jung JungiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Alyssa C. Rezey

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2 papers

Recent·Most cited

PathologyScience Translational MedicinePeer-reviewedSep 10, 2025

Loss of TIM4-Dependent Efferocytosis in Kupffer CellsPromotes Liver Fibrosis in Nonalcoholic Steatohepatitis

Hongxue Shi, Xiaobo Wang, D. Christopher Sloas…·Ira A. Tabas

This study shows that loss of TIM4 in Kupffer cells impairs efferocytosis of apoptotic hepatocytes in NASH, promoting liver fibrosis, and that restoring TIM4 reduces fibrosis.

34 citationstop 1%

humanmouse

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Cell BiologybioRxivPreprintJan 16, 2018

Phosphorylation of GMFγ by c-Abl coordinates lamellipodial and focal adhesion dynamics

Brennan D. Gerlach, Guoning Liao, Kate Tubbesing…·Dale D. Tang

This study shows that c-Abl phosphorylates GMFγ at tyrosine-104, directing N-WASP to either protrusions or focal adhesions, thereby regulating cell migration.

DOI 10.1101/248914

humanproteomics

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