ImmunologybioRxivPreprint
An IL-2 mutein increases IL-10 and CTLA-4-dependent suppression of dendritic cells by regulatory T cells
B. L. Jamison, M. Lawrance, C. J. Wang…·D. J. Campbell
The paper shows an IL-2 mutein expands regulatory T cells that enhance IL-10 and CTLA-4 to suppress dendritic cells, reducing autoimmunity in NOD mice.
DOI 10.1101/2023.12.01.569613