T Cell Repertoire Evolution After Allogeneic Bone Marrow Transplantation: An Organizational Perspective
J. Meier, M. Fawaz, H. Abdeen, J. Reed, C. Kanakry, L. Luznik, A. Toor
This study quantifies T cell repertoire reconstitution after bone marrow transplantation by analyzing TCR β sequence organization, finding reduced repertoire complexity post-transplant and preserved VJ segment symmetry.
bioRxiv · May 21, 2018Immunology