Author

H. B. Jones

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. P. Turnbull· 1 shared A. Pinto-Fernandez· 1 shared B. M. Kessler· 1 shared C. R. Pudney· 1 shared D. P. O'Brien· 1 shared D. Pantos· 1 shared D. Rasadean· 1 shared E. J. Murphy· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. P. Turnbull

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2 papers

Recent·Most cited

BiochemistrybioRxivSep 13, 2022

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

D. P. O'Brien, H. B. Jones, F. Guenther…·B. M. Kessler

This study investigates how a benzosulfonamide compound inhibits USP30, a mitochondrial deubiquitylating enzyme, using biochemical and structural methods to reveal its binding mechanism and selectivity.

DOI 10.1016/j.mcpro.2023.100609

humanproteomics

BiochemistrybioRxivJun 25, 2021

Chemical mapping exposes the importance of active site interactions in governing the temperature dependence of enzyme turnover

S. D. Winter, H. B. Jones, D. Rasadean…·C. R. Pudney

The paper maps how substrate interactions affect enzyme temperature dependence and global protein dynamics using a promiscuous enzyme.

DOI 10.1021/acscatal.1c04679

experimental assayprotein folding & dynamics