BiochemistrybioRxiv
Chemoinformatic-guided engineering of polyketide synthases
A. Zargar, R. Lal, L. Valencia…·J. D. Keasling
This study uses chemoinformatics to engineer polyketide synthases for producing saturated β-carbon compounds, finding a correlation between chemical similarity and product titers.
DOI 10.1021/jacs.0c02549