Author

A. Kothari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Mukhopadhyay· 2 shared A. C. Hernandez· 1 shared A. Loubat· 1 shared A. M. Deutschbauer· 1 shared A. P. Arkin· 1 shared A. Prieto· 1 shared A. Wong· 1 shared A. Zargar· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Mukhopadhyay

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ecogenomics of groundwater viruses suggests niche differentiation linked to specific environmental tolerance

A. Kothari, S. Roux, H. Zhang, A. Prieto, D. Soneja, J.-M. Chandonia, S. J. Spencer, X. Wu, S. Altenburg, M. W. Fields, A. M. Deutschbauer, A. P. Arkin, E. J. Alm, R. Chakraborty, A. Mukhopadhyay

The paper identifies 41 viral clusters in groundwater plasmidomes, links them to bacterial hosts, and detects novel phage genera and host-specific genes.

mSystems · Jun 29, 2021Peer-reviewedMicrobiology

STING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer

C. Pantelidou, H. Jadhav, A. Kothari, R. Liu, J. L. Guerriero, G. I. Shapiro

bioRxiv · Jan 26, 2021Cancer Biology

Chemoinformatic-guided engineering of polyketide synthases

A. Zargar, R. Lal, L. Valencia, J. Wang, T. Backman, P. Cruz-Morales, A. Kothari, M. Werts, A. Wong, C. B. Bailey, A. Loubat, Y. Liu, Y. Chen, V. Benites, S. Chang, , J. D. Keasling

This study uses chemoinformatics to engineer polyketide synthases for producing saturated β-carbon compounds, finding a correlation between chemical similarity and product titers.

bioRxiv · May 10, 2020Biochemistry

Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer

S. Bhattacharyya, C. Oon, A. Kothari, W. Horton, J. Link, R. C. Sears, M. H. Sherman

This study identifies FGF1 from cancer-associated fibroblasts as a paracrine regulator of MYC in pancreatic cancer, showing its role in MYC stability and tumor formation.

bioRxiv · Jul 22, 2019Cancer Biology