Author

H. Goar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1

Frequent Co-Authors

D. Sarkar· 4 shared P. Paul· 4 shared B. Bamniya· 3 shared H. Khan· 3 shared K. Mehta· 2 shared B. Thakur· 1 shared N. Baid· 1 shared P. R. Singh· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersMicrobiology

D. Sarkar

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Author profile →

4 papers

Recent·Most cited

Context-dependent acetylation of the virulence regulator PhoP accounts for carbon-source specific mycobacterial growth inhibition under acidic conditions

P. Paul, K. Mehta, R. Ujjainiya, B. Bamniya, B. Thakur, H. Goar, D. Sarkar

The paper shows that PhoP acetylation, influenced by acidic conditions and carbon sources, affects mycobacterial growth and virulence.

bioRxiv · Jan 25, 2024 · PreprintMicrobiology

Dual functioning by the PhoR sensor is a key determinant to Mycobacterium tuberculosis virulence

P. R. Singh, H. Goar, P. Paul, K. Mehta, B. Bamniya, V. Anil Kumar, R. Bansal, H. Khan, S. Karthikeyan, D. SARKAR

This study identifies PhoR as a dual-function sensor kinase/phosphatase in M. tuberculosis, revealing its role in virulence through pH and salt sensing and regulation of the PhoP regulon.

bioRxiv · Apr 13, 2023 · PreprintMicrobiology

Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by regulating cAMP level

H. Khan, P. Paul, H. Goar, B. Bamniya, N. Baid, D. Sarkar

The paper identifies PhoP's role in regulating cAMP levels in M. tuberculosis by repressing the PDE Rv0805, affecting stress response and intracellular survival.

bioRxiv · Mar 7, 2022Microbiology

Molecular connectivity between extra-cytoplasmic sigma factors and PhoP accounts for integrated mycobacterial stress response

H. Goar, P. Paul, H. Khan, D. SARKAR

This study investigates how PhoP interacts with sigma factors to regulate mycobacterial stress responses under different conditions, revealing distinct roles in pH and redox homeostasis.

bioRxiv · Oct 25, 2021 · PreprintMicrobiology