Generating new FANCA-deficient HNSCC cell lines by genomic editing recapitulate the cellular phenotypes of Fanconi anemia
R. Errazquin, E. Sieiro, P. Moreno, M. J. Ramirez, C. Lorz, J. Peral, J. A. Casado, F. J. Roman-Rodriguez, H. Hanenber, P. Rio, J. Surralles, C. Segrelles, R. Garcia-Escudero
The paper generates FANCA-deficient HNSCC cell lines using CRISPR/Cas9 and shows they recapitulate FA-related cellular phenotypes.
bioRxiv · Oct 3, 2020Cancer Biology