BiophysicsbioRxiv
Cantu syndrome-associated SUR2 (ABCC9) mutations in distinct structural domains result in KATP channel gain-of-function by differential mechanisms
C. McClenaghan, A. Hanson, M. Sala-Rabanal…·C. G. Nichols
This study investigates how specific SUR2 mutations in Cantu Syndrome alter KATP channel function through different mechanisms, with implications for drug response.
DOI 10.1074/jbc.ra117.000351