AP-4 mediates vesicular transport of the 2-AG endocannabinoid producing enzyme DAGLB
A. K. Davies, M. Ziegler, H. Jumo, W. Afshar Saber, D. Ebrahimi-Fakhari, G. H. H. Borner
The paper identifies DAGLB as an AP-4 cargo, showing its axonal targeting and role in 2-AG signaling, which may explain axon growth defects in AP-4 deficiency.
bioRxiv · Oct 25, 2020 · PreprintCell Biology