The actin binding protein profilin 1 is critical for mitochondria function
T.-A. Read, B. A. Cisterna, K. Skruber, S. Ahmadieh, H. L. Lindamood, J. A. Vitriol, Y. Shi, A. E. Y. T. Lefebvre, J. B. Black, M. T. Butler, J. E. Bear, A. Cherezova, D. V. Ilatovskaya, N. L. Weintraub, E. A. Vitriol
This study identifies a novel role for profilin 1 in regulating mitochondria function and reveals a potential pathogenic mechanism for ALS-linked PFN1 variants.
bioRxiv · Aug 7, 2023Cell Biology