Author

H. Maat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:clustering· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Vellenga· 2 shared G. Huls· 2 shared J. J. Schuringa· 2 shared J. Jaques· 2 shared A. Bertin· 1 shared A. Brouwers-Vos· 1 shared A. Rodriguez Lopez· 1 shared C. Gravesteijn· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. Vellenga

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Rural populations exposed to Ebola Virus Disease respond positively to localised case handling: evidence from Sierra Leone

E. Y. Mokuwa, H. Maat

This paper examines community responses to Community Care Centres (CCC) in Sierra Leone during the 2014-15 Ebola epidemic, finding they were generally well accepted and improved reporting and treatment outcomes.

PLOS Neglected Tropical Diseases · Jan 21, 2020Peer-reviewedScientific Communication & Education

USP7 as part of non-canonical PRC1.1 is a druggable target in leukemia

H. Maat, J. Jaques, A. Rodriguez Lopez, S. Hogeling, M. P. de Vries, C. Gravesteijn, A. Brouwers-Vos, G. Huls, E. Vellenga, V. van den Boom, J. J. Schuringa

This study identifies USP7 as a therapeutic target in leukemia, particularly in TP53-mutated AML, by showing its role in non-canonical PRC1.1 complex stability and function.

bioRxiv · Jul 9, 2019Cancer Biology

Using a lentiviral Tet-regulated miR-E shRNA dual color vector to evaluate gene function in human leukemic stem cells in vivo

H. Maat, J. Jaques, E. Vellenga, G. Huls, V. Schuringa, J. J. Schuringa

This study uses a lentiviral vector to inducibly knock down PCGF1 in human leukemia models, showing that timing of gene repression affects treatment efficacy and clonal drift in leukemic stem cells.

bioRxiv · Jul 8, 2019 · PreprintCancer Biology

Hidden Rice Diversity in the Guianas

T. van Andel, M. Veltman, A. Bertin, H. Maat, T. Polime, D. Hille Ris Lambers, J. Tjoe Awie, H. J. De Boer, V. Manzanilla

This study identifies 50 rice varieties cultivated by Maroons in the Guianas, 15 of which are new, revealing hidden genetic diversity maintained through cultural practices despite external pressures.

bioRxiv · Feb 28, 2019Plant Biology