Plasma Oxylipin Profiling by High Resolution Mass Spectrometry Reveal Signatures of Inflammation and Hypermetabolism in Amyotrophic Lateral Sclerosis
A. B. Chaves-Filho, L. S. Diniz, R. S. Santos, R. S. Lima, H. Oreliana, I. F. D. Pinto, L. S. Dantas, A. Inague, R. L. Faria, M. H. G. Medeiros, I. Glezer, W. T. Festuccia, M. Y. Yoshinaga, S. Miyamoto
This paper develops a high-throughput LC-HRMS method to analyze oxylipins in ALS rat models and identifies altered oxylipin profiles associated with inflammation and hypermetabolism.
bioRxiv · Jul 7, 2023Biochemistry