Author

H. Raphel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

C. Kumar-Sinha· 1 shared C. M. Julian· 1 shared E. Mukherjee· 1 shared J. D. Daley· 1 shared K. A. Janeway· 1 shared K. M. Bailey· 1 shared K. Weiss· 1 shared L. M. Maurer· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. Kumar-Sinha

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1 paper

Recent·Most cited

PARP inhibition in Ewing sarcoma: impact of germline DNA damage repair defects and activation of immunoregulatory pathways

L. M. Maurer, R. E. Venier, E. Mukherjee, C. M. Julian, J. D. Daley, N. G. Bailey, M. F. Jacobs, C. Kumar-Sinha, H. Raphel, K. Weiss, K. A. Janeway, R. Mody, P. C. Lucas, L. M. McAllister-Lucas, K. M. Bailey

This study shows that Ewing sarcoma cells with germline BARD1 mutations are sensitive to PARP inhibitors and that PARP inhibition increases PD-L1 expression, suggesting potential for combination immunotherapy.

bioRxiv · Sep 18, 2020 · PreprintCancer Biology