Author

K. Weiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. Huisken· 2 shared A. A. Hakimi· 1 shared A. Huttenlocher· 1 shared A. J. Gill· 1 shared A. Velten· 1 shared A. Yoo· 1 shared B. Freeman· 1 shared C. B. Stanley· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBioengineering

J. Huisken

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array

K. Samimi, D. E. Desa, W. Lin, K. Weiss, J. Li, J. Huisken, V. Miskolci, A. Huttenlocher, J. V. Chacko, A. Velten, J. D. Rogers, K. W. Eliceiri, M. C. Skala

This paper introduces a light sheet FLIM system using SPAD arrays for fast, label-free single-cell NAD(P)H autofluorescence imaging in live cells and organisms.

bioRxiv · Feb 1, 2023Bioengineering

Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi

P. M. Airs, K. Vaccaro, K. J. Gallo, N. Dinguirard, Z. W. Heimark, N. J. Wheeler, J. He, K. Weiss, N. E. Schroeder, J. Huisken, M. Zamanian

The paper uses spatial transcriptomics to identify antiparasitic targets in Brugia malayi head tissues, revealing new drug and vaccine candidates.

bioRxiv · Aug 24, 2021Microbiology

Genomic and Metabolic Hallmarks of SDH- and FH-Deficient Renal Cell Carcinomas

A. Yoo, C. Tang, M. Zucker, K. Fitzgerald, P. M. Rappold, K. Weiss, B. Freeman, C.-H. Lee, N. Schultz, R. Motzer, P. Russo, J. Coleman, V. E. Reuter, Y.-B. Chen, M. I. Carlo, , E. Reznik

This study compares the genomic and metabolic features of SDH- and FH-deficient renal cell carcinomas, identifying distinct genetic and metabolic abnormalities.

bioRxiv · Jun 9, 2021Cancer Biology

Small-angle neutron scattering solution structures of NADPH-dependent sulfite reductase

D. T. Murray, K. Weiss, C. B. Stanley, G. Nagy, M. E. Stroupe

The paper reports the first solution structures of sulfite reductase heterodimers using small-angle neutron scattering, showing how subunit binding and oxidation state affect conformation and electron transfer.

bioRxiv · Dec 8, 2020Biochemistry

PARP inhibition in Ewing sarcoma: impact of germline DNA damage repair defects and activation of immunoregulatory pathways

L. M. Maurer, R. E. Venier, E. Mukherjee, C. M. Julian, J. D. Daley, N. G. Bailey, M. F. Jacobs, C. Kumar-Sinha, H. Raphel, K. Weiss, K. A. Janeway, R. Mody, P. C. Lucas, L. M. McAllister-Lucas, K. M. Bailey

This study shows that Ewing sarcoma cells with germline BARD1 mutations are sensitive to PARP inhibitors and that PARP inhibition increases PD-L1 expression, suggesting potential for combination immunotherapy.

bioRxiv · Sep 18, 2020 · PreprintCancer Biology