Unique and redundant roles of SOX2 and SOX17 in regulating the germ cell tumour fate
S. Jostes, M. Fellermeyer, G. Merges, G. Kristiansen, D. Nettersheim, H. Schorle
This study compares SOX17 and SOX2 binding patterns in germ cell tumors and somatic cells, showing SOX17 maintains pluripotency in seminomas while SOX2 does so in embryonal carcinomas.
International Journal of Cancer · Nov 1, 2019Peer-reviewedCancer Biology