Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity
U. Rand, S. Y. Kupke, H. Shkarlet, M. D. Hein, T. Hirsch, P. Marichal-Gallardo, L. Cicin-Sain, U. Reichl, D. Bruder
This study shows that influenza A virus defective interfering particles inhibit SARS-CoV-2 replication in vitro by enhancing innate immunity through JAK/STAT signaling.
bioRxiv · Feb 19, 2021Microbiology