Author

U. Reichl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

S. Y. Kupke· 3 shared D. Benndorf· 2 shared M. D. Hein· 2 shared M. Wolf· 2 shared R. Heyer· 2 shared Y. Genzel· 2 shared A. Bassignani· 1 shared A. Beblek· 1 shared

Activity by Year

2021-2024 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersEvolutionary Biology

S. Y. Kupke

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivity

C. B. Karsten, F. F. R. Buttner, S. Cajic, I. Nehlmeier, B. Roshani, A. Klippert, U. Sauermann, N. Stolte-Leeb, U. Reichl, R. Gerardy-Schahn, E. Rapp, C. Stahl-Hennig, S. Pohlmann

This study compares glycosylation, infectivity, and neutralization sensitivity of SIV produced in macrophages versus CD4+ T cells, revealing differences in glycan profiles and their impact on viral spread and antibody neutralization.

bioRxiv · Jan 2, 2024Microbiology

Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy

L. Pelz, D. Ruediger, T. Dogra, F. G. Alnaji, Y. Genzel, C. B. Brooke, S. Y. Kupke, U. Reichl

This study investigates the competition between influenza A virus and its defective interfering particles (DIPs) during co-infection, identifying DIPs with superior antiviral efficacy as potential therapeutic candidates.

Journal of Virology · Nov 23, 2021Peer-reviewedEvolutionary Biology

Cell culture-based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system

M. D. Hein, A. Chawla, M. Cattaneo, S. Y. Kupke, Y. Genzel, U. Reichl

This paper establishes an automated perfusion process for producing IAV DIPs using an alternating tangential flow filtration system, achieving high DIP titers and enabling continuous virus harvesting.

bioRxiv · Jun 7, 2021Bioengineering

Integrated cycles for urban biomass as a strategy to promote a CO2-neutral society - A feasibility study

N. Meinusch, S. Kramer, O. Koerner, I. Seick, J. Wiese, A. Beblek, R. Berges, B. Illenberger, M. Illenberger, J. Uebbing, M. Wolf, G. Saake, D. Benndorf, U. Reichl, R. Heyer

This paper evaluates the feasibility of integrating closed biomass cycles into residential buildings to achieve CO2 neutrality, showing technical viability but higher costs compared to revenues.

bioRxiv · Apr 22, 2021Bioengineering

Critical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows

T. Van Den Bossche, B. J. Kunath, K. Schallert, S. S. Schäpe, P. E. Abraham, J. Armengaud, M. O. Arntzen, A. Bassignani, D. Benndorf, S. Fuchs, R. J. Giannone, T. J. Griffin, L. H. Hagen, R. Halder, C. Henry, , Marte

CAMPI evaluates metaproteomic workflows across labs, finding sample processing drives peptide variability while workflows yield similar functional profiles.

bioRxiv · Mar 5, 2021Microbiology

Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity

U. Rand, S. Y. Kupke, H. Shkarlet, M. D. Hein, T. Hirsch, P. Marichal-Gallardo, L. Cicin-Sain, U. Reichl, D. Bruder

This study shows that influenza A virus defective interfering particles inhibit SARS-CoV-2 replication in vitro by enhancing innate immunity through JAK/STAT signaling.

bioRxiv · Feb 19, 2021Microbiology