Author

H. Sicht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Organism:virus· 1

Frequent Co-Authors

E. Socher· 1 shared F. Paulsen· 1 shared F. Zunke· 1 shared L. Heger· 1 shared M. Conrad· 1 shared P. Arnold· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

E. Socher

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Mutations in the B.1.1.7 SARS-CoV-2 spike protein reduce receptor-binding affinity and induce a flexible link to the fusion peptide

E. Socher, M. Conrad, L. Heger, F. Paulsen, H. Sicht, F. Zunke, P. Arnold

This paper uses molecular dynamics simulations to show that B.1.1.7 SARS-CoV-2 mutations reduce ACE2 binding affinity and increase flexibility near the fusion peptide, potentially contributing to higher infectivity.

bioRxiv · Apr 6, 2021Biophysics