Author

H. von Gruning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Reader· 2 shared L.-M. Birkholtz· 2 shared A. Smit· 1 shared B. Brider· 1 shared C. Abrie· 1 shared C. Doerig· 1 shared H. Painter· 1 shared J. Niemand· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

J. Reader

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2 papers

Recent·Most cited

Multistage activity within a diverse set of epi-drugs against Plasmodium falciparum parasites

N. Coetzee, H. von Gruning, M. van der Watt, J. Reader, L.-M. Birkholtz

The paper evaluates 95 epigenetic modulators for activity against different stages of Plasmodium falciparum, finding some compounds effective against multiple stages and with transmission-blocking potential.

bioRxiv · Jul 4, 2019 · PreprintBiochemistry

Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites.

R. A. Van Biljon, J. Niemand, R. D. van Wyk, K. Clark, B. Brider, C. Abrie, H. Von Gruning, W. Smidt, A. Smit, J. Reader, H. Painter, M. Llinas, C. Doerig, L.-M. Birkholtz

This paper induces and reverses cell cycle arrest in Plasmodium falciparum using DFMO and polyamines, revealing gene expression changes linked to cell cycle re-entry.

bioRxiv · Aug 3, 2018Cell Biology