K. Clark

Macro-environment strongly interacts with warming in a global analysis of decomposition

This study analyzes decomposition responses to warming across global macro-environmental gradients, finding that warming effects vary significantly depending on moisture and temperature, with a threshold of 5.2°C for significant decomposition increase.

A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

This study identifies a nonenzymatic role of IRE1 in cancer cell cycle progression and tumor growth, independent of its kinase-RNase activity.

Insights from a survey of mentorship experiences by graduate and postdoctoral researchers

This study surveys graduate and postdoctoral researchers to assess mentorship quality, finding dissatisfaction in 25-45% of respondents and identifying common issues and strategies to improve mentorship.

The faculty-to-faculty mentorship experience: a survey on challenges and recommendations for improvements

This study surveys early- and mid-career faculty to assess mentorship experiences, identifying challenges and recommending improvements for faculty mentorship programs.

Tensin3 interaction with talin drives formationof fibronectin-associated fibrillar adhesions

This study identifies tensin3's interaction with talin as essential for fibronectin fibrillogenesis and integrin-associated fibrillar adhesions.

Characterization of gene repression by designed transcription activator-like effector dimer proteins

The paper quantitatively characterizes gene repression in E. coli using designed TALED proteins and compares them to natural lac repressor loops.

Ancestral absence of electron transport chains in Patescibacteria and DPANN

The paper investigates Patescibacteria and DPANN, finding they lack electron transport chains and rely on fermentation, suggesting ancestral adaptations to symbiotic lifestyles.

Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma

This study shows that disrupting IRE1α's kinase domain reduces multiple myeloma tumor growth and enhances treatment efficacy, suggesting it as a therapeutic target.

Inducing controlled cell cycle arrest and re-entry during asexual proliferation of Plasmodium falciparum malaria parasites.

This paper induces and reverses cell cycle arrest in Plasmodium falciparum using DFMO and polyamines, revealing gene expression changes linked to cell cycle re-entry.